FB2026_02 , released June 18, 2026
Allele: Dmel\kmgΔ7
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General Information
Symbol
Dmel\kmgΔ7
Species
D. melanogaster
Name
FlyBase ID
FBal0326480
Feature type
allele
Associated gene
Dmel\kmg
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
CRISPR/Cas9
(Kim et al., 2017)
Progenitor genotype
Cytology
Description

A 7 bp deletion after the 31st base pair from the start codon, which introduces a premature stop codon at the position of the 45th amino acid.

(Kim et al., 2017)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
deletion
2L:13,160,837..13,160,843 [+]
Comment:

A seven bp deletion causes a frameshift and early translation termination after the addition of 34 novel amino acids. Translation is postulated to occur from an internal start codon in the mutant.

(Kim et al., 2017)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      kmgΔ7/Df(2L)ED779 mutants are viable, female-fertile but male sterile - the male testes display accumulation of mature primary spermatocytes arrested just before transition to meiosis I.

      (Kim et al., 2017)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescued by

      kmgΔ7/Df(2L)ED779 is rescued by kmg+t4.3

      (Kim et al., 2017)
      Comments

      The differentiation defects, meiotic arrest and sterility characteristic for kmgΔ7/Df(2L)ED779 males are rescued by combination with kmg+t4.3.

      (Kim et al., 2017)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      kmgΔ7
      (Kim et al., 2017)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)