FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Ptp52FCS.UAS.Tag:HA
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General Information
Symbol
Dmel\Ptp52FCS.UAS.Tag:HA
Species
D. melanogaster
Name
FlyBase ID
FBal0326620
Feature type
allele
Associated gene
Dmel\Ptp52F
Associated Insertion(s)
Carried in Construct
P{UAS-Ptp52F.CS.HA}
Key Links
Transgenic product class
missense_variant
(Santhanam et al., 2014)
Mutagen
Nature of the Allele
Transgenic product class
missense_variant
(Santhanam et al., 2014)
Mutagen
in vitro construct
(Santhanam et al., 2014)
Progenitor genotype
Carried in construct
P{UAS-Ptp52F.CS.HA}
Cytology
Description

UAS regulatory sequences drive expression of a phosphatase-dead mutant form of Ptp52F (carries the C1290S mutation) that is tagged with Tag:HA.

(Santhanam et al., 2014)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Ptp52F
Tagged with
Tag:HA
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      The histolysis of larval midgut and the removal of the gastric caeca, which occur during metamorphosis, are delayed in a significant proportion of individuals expressing Ptp52FCS.Scer\UAS.T:Ivir\HA1, either under the control of Scer\GAL4Myo31DF-NP0001 or under the combined control of Scer\GAL4tub.PU and Gal80[ts] for induction only from the second instar larval stage onwards, as compared to controls.

      (Santhanam et al., 2014)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The delays in the removal of the gastric caeca and in the histolysis of larval midgut during metamorphosis resulting from the expression of Ptp52FCS.Scer\UAS.T:Ivir\HA1 under the control of Scer\GAL4Myo31DF-NP0001 is suppressed by the co-expression of TER94Scer\UAS.T:Zzzz\FLAG.

      (Santhanam et al., 2014)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Ptp52FCS.Scer\UAS.T:Ivir\HA1
      Ptp52FCS.UAS.Tag:HA
      Name Synonyms
      Secondary FlyBase IDs
        References (1)