FB2026_02 , released June 18, 2026
Allele: Dmel\ATP7DEL.EGFP
Open Close
General Information
Symbol
Dmel\ATP7DEL.EGFP
Species
D. melanogaster
Name
FlyBase ID
FBal0326631
Feature type
allele
Associated gene
Dmel\ATP7
Associated Insertion(s)
Carried in Construct
M{gATP7-EGFP.DEL}
Key Links
Transgenic product class
inframe_deletion
(Mercer et al., 2017)
Mutagen
Nature of the Allele
Transgenic product class
inframe_deletion
(Mercer et al., 2017)
Mutagen
in vitro construct
(Mercer et al., 2017)
Progenitor genotype
Carried in construct
M{gATP7-EGFP.DEL}
Cytology
Description

A genomic fragment (Pacman clone CH3222-77E05) containing the entire ATP7 gene, which has been mutated to result in a deletion of amino acid residues 511-512. A EGFP tag has been inserted at the C-terminal end of the ATP7 open reading frame.

(Mercer et al., 2017)
Allele components
Component
Use(s)
Regulatory region(s)
ATP7
Encoded product / tool
ATP7
Tagged with
EGFP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to rescue

      ATP7DEL.EGFP fails to rescue ATP7ΔP17

      (Mercer et al., 2017)
      Comments

      The lethality of ATP7ΔP17/Y hemizygous males cannot be rescued by combination with ATP7DEL.T:Avic\GFP-EGFP. Although combination with ATP7DEL.T:Avic\GFP-EGFP partially rescues the minimal post-hatching growth of ATP7ΔP17 mutant male larvae it has no appreciable effect on the mouthpart development and pigmentation defects.

      (Mercer et al., 2017)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      ATP7DEL.EGFP
      ATP7DEL.T:Avic\GFP-EGFP
      Name Synonyms
      Secondary FlyBase IDs
        References (1)