FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\IdhUAS.c.Tag:HA
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General Information
Symbol
Dmel\IdhUAS.c.Tag:HA
Species
D. melanogaster
Name
FlyBase ID
FBal0328282
Feature type
allele
Associated gene
Dmel\Idh
Associated Insertion(s)
Carried in Construct
P{UAS-Idh.c.HA}
Key Links
Transgenic product class
cDNA
(Yang et al., 2017)
wild_type
(Yang et al., 2017)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Yang et al., 2017)
wild_type
(Yang et al., 2017)
Mutagen
in vitro construct
(Yang et al., 2017)
Progenitor genotype
Carried in construct
P{UAS-Idh.c.HA}
Cytology
Description

UASt regulatory sequences drive expression of a cytosolic isoform of Idh (cDNA from AT04910 BDGP clone), tagged at the C-terminal with Tag:HA.

(Yang et al., 2017)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Idh
Tagged with
Tag:HA
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      NOT Suppressor of
      Phenotype Manifest In
      NOT Suppressor of
      Statement
      Reference

      Scer\GAL4ple.PF/IdhUAS.c.Tag:HA is a non-suppressor of dopaminergic neuron | adult stage phenotype of Pink1B9

      (Yang et al., 2017)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Expression of IdhScer\UAS.c.T:Ivir\HA1 cannot rescue either the locomotor deficit (with the Scer\GAL4da.PU driver) or the loss of brain dopaminergic neurons (with Scer\GAL4ple.PF) characteristic for Pink1B9 mutant adult flies.

      (Yang et al., 2017)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      IdhScer\UAS.c.T:Ivir\HA1
      IdhUAS.c.Tag:HA
      Name Synonyms
      Secondary FlyBase IDs
        References (1)