FB2026_02 , released June 18, 2026
Allele: Dmel\moonFS2-Δ28
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General Information
Symbol
Dmel\moonFS2-Δ28
Species
D. melanogaster
Name
FlyBase ID
FBal0335656
Feature type
allele
Associated gene
Dmel\moon
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
CRISPR/Cas9
(Andersen et al., 2017)
Progenitor genotype
Cytology
Description

Frameshift allele resulting in a truncated protein.

(Andersen et al., 2017)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      moonFS2-Δ28/moonFS1-Δ1 transheterozygotes are viable, their ovaries have an apparently normal morphology, but are sterile.

      (Andersen et al., 2017)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressed by
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The female sterility of moonFS1-Δ1/moonFS2-Δ28 transheterozygotes is partially suppressed by the combination of delnos.T:Zzzz\vhhGFP4 and Trf2s.nos.LAP, as the great majority of embryos undergo gastrulation and only about a third hatch into larva.

      (Andersen et al., 2017)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      moonFS-Δ28
      moonFS2-Δ28
      moonFS2_Δ28
      (Andersen et al., 2017)
      moonΔ28
      (Chen et al., 2021)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)