FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
Allele: Dmel\MembrinUAS.Tag:FLAG
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General Information
Symbol
Dmel\MembrinUAS.Tag:FLAG
Species
D. melanogaster
Name
FlyBase ID
FBal0335730
Feature type
allele
Associated gene
Dmel\Membrin
Associated Insertion(s)
Carried in Construct
M{UAS-Membrin.FLAG}
Key Links
Transgenic product class
wild_type
(Praschberger et al., 2017)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Praschberger et al., 2017)
Mutagen
in vitro construct
(Praschberger et al., 2017)
Progenitor genotype
Carried in construct
M{UAS-Membrin.FLAG}
Cytology
Description

UAS regulatory sequences drive expression of Membrin, tagged at the N-terminal with Tag:FLAG.

(Praschberger et al., 2017)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Membrin
Tagged with
Tag:FLAG
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      The expression of MembrinScer\UAS.T:Zzzz\FLAG alone under the control of either Scer\GAL4da.G32, Scer\GAL4elav.PU or Scer\GAL4nSyb.PS does not lead to eclosion defects, as compared to controls.

      The expression of MembrinScer\UAS.T:Zzzz\FLAG alone under the control of Scer\GAL4da.G32 does not lead to synapse defects in third instar larval neuromuscular junctions, as compared to controls.

      (Praschberger et al., 2017)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Scer\GAL4da.G32/MembrinUAS.Tag:FLAG rescues Membrin1524

      (Praschberger et al., 2017)

      Scer\GAL4da.G32/MembrinUAS.Tag:FLAG rescues MembrinGD2313

      (Praschberger et al., 2017)
      Comments

      The expression of MembrinScer\UAS.T:Zzzz\FLAG under the control of Scer\GAL4da.G32 rescues both the larval lethality exhibited by Membrin1524 homozygotes and the pupal lethality of individuals expressing MembrinGD2313 under the control of Scer\GAL4da.G32.

      (Praschberger et al., 2017)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      MembrinScer\UAS.T:Zzzz\FLAG
      MembrinUAS.Tag:FLAG
      Name Synonyms
      Secondary FlyBase IDs
        References (1)