FB2026_02 , released June 18, 2026
Allele: Dmel\BalatmCherry
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General Information
Symbol
Dmel\BalatmCherry
Species
D. melanogaster
Name
FlyBase ID
FBal0336285
Feature type
allele
Associated gene
Dmel\Balat
Associated Insertion(s)
TI{mCherry}BalatmCherry
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
CRISPR/Cas9
(Han et al., 2017)
Progenitor genotype
Associated Insertion(s)
TI{mCherry}BalatmCherry
Cytology
Description

The mCherry coding sequence (including a stop codon at the C-terminal end) has been introduced into the Balat locus, replacing an N-terminal portion of the Balat coding sequence. This results in mCherry being expressed under the control of native Balat regulatory sequences. A single loxP site is present upstream of the mCherry sequence.

(Han et al., 2017)
Allele components
Component
Use(s)
Inserted element
TI{mCherry}
Encoded product / tool
mCherry
Also carries
loxP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      adult stage
      pigment cell
      (Han et al., 2017)
      Additional Information
      Statement
      Reference

      Reporter expression is observed predominantly in the retinal pigment cells in the eye.

      (Han et al., 2017)
       
      Marker for
      Reflects expression of
      Balat
      (Han et al., 2017)
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      BalatmCherry homozygosity virtually abolishes the normal electroretinogram ON and OFF transients upon light stimulation, as compared to controls.

      (Han et al., 2017)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      BalatmCherry
      Name Synonyms
      Secondary FlyBase IDs
        References (1)