FB2026_02 , released June 18, 2026
Allele: Dmel\Spn77BcSK1
Open Close
General Information
Symbol
Dmel\Spn77BcSK1
Species
D. melanogaster
Name
FlyBase ID
FBal0336443
Feature type
allele
Associated gene
Dmel\Spn77Bc
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
CRISPR/Cas9
(Kondo et al., 2017)
Progenitor genotype
Cytology
Description

A frameshift allele that truncates the majority of the coding potential of the gene.

(Kondo et al., 2017)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
delins
3L:20,342,924..20,342,927 [+]
Inserted_sequence:

GTCACTTATGATCACTTATG

Comment:

Replacement of TCCA with GTCACTTATGATCACTTATG for a net insertion of 20 nucleotides in the Spn77Bc coding region.

(Kondo et al., 2017)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Spn77BcSK1 mutant adults do not show any overt morphological defects, but the males show significant increase in the frequency of spermatid individualization defects and high proportion of abnormal individualization complexes.

      (Kondo et al., 2017)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Spn77BcSK1
      Name Synonyms
      Secondary FlyBase IDs
        References (1)