FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\upΔmir-9a.UAS.10b
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General Information
Symbol
Dmel\upΔmir-9a.UAS.10b
Species
D. melanogaster
Name
FlyBase ID
FBal0336598
Feature type
allele
Associated gene
Dmel\up
Associated Insertion(s)
Carried in Construct
P{UAS-up.10b.Δmir-9a}
Key Links
Transgenic product class
wild_type
(Katti et al., 2017)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Katti et al., 2017)
Mutagen
in vitro construct
(Katti et al., 2017)
Progenitor genotype
Carried in construct
P{UAS-up.10b.Δmir-9a}
Cytology
Description

UASt regulatory sequences drive expression of the pupal isoform (10b) of up cDNA lacking the mir-9a binding site.

(Katti et al., 2017)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
up
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The severe dorsal longitudinal muscle structural defects, along with the sarcomere disorganization and to a large extent also the flightlessness observed in adult flies expressing mir-9aScer\UAS.T:Ppyr\LUC under the control of Scer\GAL4Hk-UH3 are rescued by co-expression of upΔmir-9a.Scer\UAS.10b.

      (Katti et al., 2017)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      upΔmir-9a.Scer\UAS.10b
      upΔmir-9a.UAS.10b
      Name Synonyms
      Secondary FlyBase IDs
        References (1)