FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\barcm4-2
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General Information
Symbol
Dmel\barcm4-2
Species
D. melanogaster
Name
FlyBase ID
FBal0337819
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Progenitor genotype
Cytology
Description

Deletion in exon 2, resulting in a frameshift and a premature stop codon.

Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Comment:

A one base deletion leads to a frameshift after amino acid 113.

Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

barcm4-2 somatic clones of both type I and type II neuroblast lineages exhibit a significant decrease in the total number of cells compared to controls. Type II neuroblast lineage clones are mostly composed of intermediate neural progenitors and comparatively few neurons, but exhibit no significant difference in the total number of intermediate neural progenitors per clone, as compared to controls; these clones exhibit a significant increase in the number of immature Ase-positive, Dpn-negative intermediates and, conversely, a significant decrease of Ase-positive, Dpn-positive, as compared to controls. Type I neuroblast lineage clones exhibit a significant increase in the number of ganglion mother cells, as compared to controls.

External Data
Interactions
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Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Name Synonyms
Secondary FlyBase IDs
    References (2)