FB2026_02 , released June 18, 2026
Allele: Dmel\CaMKIIFlyFos025846
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General Information
Symbol
Dmel\CaMKIIFlyFos025846
Species
D. melanogaster
Name
FlyBase ID
FBal0337893
Feature type
allele
Associated gene
Dmel\CaMKII
Associated Insertion(s)
Carried in Construct
P{FlyFos025846}
Key Links
Transgenic product class
genomic_DNA
(Kuklin et al., 2017)
wild_type
(Kuklin et al., 2017)
Mutagen
Nature of the Allele
Transgenic product class
genomic_DNA
(Kuklin et al., 2017)
wild_type
(Kuklin et al., 2017)
Mutagen
in vitro construct
(Kuklin et al., 2017)
Progenitor genotype
Carried in construct
P{FlyFos025846}
Cytology
Description

Genomic fragment of approximately 42.5kb which encompasses the entire CaMKII transcription unit plus ~20kb upstream and ~3.3kb downstream sequence.

(Kuklin et al., 2017)
Allele components
Component
Use(s)
Regulatory region(s)
CaMKII
Encoded product / tool
CaMKII
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      CaMKIIFlyFos025846 rescues CaMKIIstopw+

      (Kuklin et al., 2017)
      Comments

      Combination with CaMKIIFlyFos025846 rescues the lethality of CaMKIIstopw+ homozygotes and the spontaneous activity at the neuromuscular junction of the rescue larvae (rate of miniature excitatory junction potentials, mEJPs) is comparable to wild-type controls.

      (Kuklin et al., 2017)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      CaMKIIFlyFos025846
      Name Synonyms
      Secondary FlyBase IDs
        References (1)