FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Mms19EGFP
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General Information
Symbol
Dmel\Mms19EGFP
Species
D. melanogaster
Name
FlyBase ID
FBal0338028
Feature type
allele
Associated gene
Dmel\Mms19
Associated Insertion(s)
Carried in Construct
M{Mms19-EGFP}
Key Links
Transgenic product class
genomic_DNA
(Nag et al., 2018)
wild_type
(Nag et al., 2018)
Mutagen
Nature of the Allele
Transgenic product class
genomic_DNA
(Nag et al., 2018)
wild_type
(Nag et al., 2018)
Mutagen
in vitro construct
(Nag et al., 2018)
Progenitor genotype
Carried in construct
M{Mms19-EGFP}
Cytology
Description

A genomic fragment that contains the Mms19 coding region along with 432bp of 5' and 372bp of 3' flanking sequence. The coding region is tagged at the C-terminal end with EGFP.

(Nag et al., 2018)
Allele components
Component
Use(s)
Regulatory region(s)
Mms19
Encoded product / tool
Mms19
Tagged with
EGFP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Mms19EGFP rescues Mms19EY00797/Df(3R)ED5147

      (Nag et al., 2018)
      Comments

      Combination with one or two copies of Mms19EGFP rescues the lethality of Mms19EY00797/Df(3R)ED5147 mutants. Expression of Mms19EGFP in Mms19EY00797 germline mutant females (created using the OvoD technique) at least partially rescues all of the various cell cycle defects (spindle defects, kinked axis of division, many missing nuclei, elongated spindle in metaphase, chromosome segregation defects, and centrosomal defects) observed in their progeny at embryonic division cycle 10-13.

      (Nag et al., 2018)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Mms19EGFP
      Mms19T:Avic\GFP-EGFP
      Name Synonyms
      Secondary FlyBase IDs
        References (1)