FlyBase Allele Report: Dmel\da[da-da.cWa.UAS]

General Information

Symbol

Dmel\da^{da-da.cWa.UAS}

Species

D. melanogaster

Name

FlyBase ID

FBal0340367

Feature type

allele

Associated gene

Dmel\da

Associated Insertion(s)

Carried in Construct

P{UAS-da.da.W}

Also Known As

UAS-da-da

Key Links

Transgenic product class

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

Mutagen

in vitro construct

(Wang and Baker, 2015)

Progenitor genotype

Carried in construct

P{UAS-da.da.W}

Cytology

Description

UASt regulatory sequences drive expression of two da monomer open reading frames (710aa and 709aa), joined in frame via a flexible Gly/Ser rich linker.

(Wang and Baker, 2015)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal cell number | larval stage, with Scer\GAL4^lz-gal4

(Reddy Onteddu et al., 2024)

abnormal neuroanatomy | larval stage, with Scer\GAL4^GMR.PU

(Reddy Onteddu et al., 2024)

increased cell number | larval stage, with Scer\GAL4^GMR.PU

(Reddy Onteddu et al., 2024)

visible | adult stage, with Scer\GAL4^lz-gal4

(Reddy Onteddu et al., 2024)

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

Scer\GAL4^lz-gal4, da^{da-da.cWa.UAS} has visible | adult stage phenotype, suppressible by Rap1^{Q63E.UASp.GFP}, Scer\GAL4^lz-gal4

(Reddy Onteddu et al., 2024)

Scer\GAL4^lz-gal4, da^{da-da.cWa.UAS} has visible | adult stage phenotype, suppressible by RapGAP1^JF01766, Scer\GAL4^lz-gal4

(Reddy Onteddu et al., 2024)

Phenotype Manifest In

Suppressed by

Statement

Reference

Scer\GAL4^lz-gal4, da^{da-da.cWa.UAS} has eye phenotype, suppressible by Rap1^{Q63E.UASp.GFP}, Scer\GAL4^lz-gal4

(Reddy Onteddu et al., 2024)

Scer\GAL4^lz-gal4, da^{da-da.cWa.UAS} has interommatidial bristle | adult stage phenotype, suppressible by Rap1^{Q63E.UASp.GFP}, Scer\GAL4^lz-gal4

(Reddy Onteddu et al., 2024)

Scer\GAL4^lz-gal4, da^{da-da.cWa.UAS} has eye phenotype, suppressible by RapGAP1^JF01766, Scer\GAL4^lz-gal4

(Reddy Onteddu et al., 2024)

Scer\GAL4^lz-gal4, da^{da-da.cWa.UAS} has interommatidial bristle | adult stage phenotype, suppressible by RapGAP1^JF01766, Scer\GAL4^lz-gal4

(Reddy Onteddu et al., 2024)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

da^{da-da.cWa.UAS}

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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