FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\spheUAS.Tag:MYC
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General Information
Symbol
Dmel\spheUAS.Tag:MYC
Species
D. melanogaster
Name
FlyBase ID
FBal0340382
Feature type
allele
Associated gene
Dmel\sphe
Associated Insertion(s)
Carried in Construct
P{UAS-sphe.Myc}
Key Links
Transgenic product class
cDNA
(Patrnogic and Leclerc, 2017)
wild_type
(Patrnogic and Leclerc, 2017)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Patrnogic and Leclerc, 2017)
wild_type
(Patrnogic and Leclerc, 2017)
Mutagen
in vitro construct
(Patrnogic and Leclerc, 2017)
Progenitor genotype
Carried in construct
P{UAS-sphe.Myc}
Cytology
Description

UAS regulates expression of sphe cDNA clone (LP05929) with a C-terminal Tag:MYC tag.

(Patrnogic and Leclerc, 2017)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
sphe
Tagged with
Tag:MYC
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      The expression of spheUAS.Tag:MYC under the control of Scer\GAL4Act5C.PU does not significantly improve the survival upon infection with the Gram-positive bacterium Enterococcus faecalis, as compared to controls.

      (Patrnogic and Leclerc, 2017)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The expression of spheUAS.Tag:MYC under the control of Scer\GAL4Act5C.PU suppresses the increased mortality to Enterococcus faecalis observed in Df(1)spheΔ49 mutants.

      (Patrnogic and Leclerc, 2017)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Scer\GAL4Act5C.PU/spheUAS.Tag:MYC rescues spheΔ104

      (Patrnogic and Leclerc, 2017)
      Comments

      The expression of spheUAS.Tag:MYC under the control of Scer\GAL4Act5C.PU rescues the increased mortality to Enterococcus faecalis observed in spheΔ104 mutants.

      (Patrnogic and Leclerc, 2017)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      spheUAS.Tag:MYC
      Name Synonyms
      Secondary FlyBase IDs
        References (1)