FB2026_02 , released June 18, 2026
Allele: Avic\GFPUAS.Tag:MCP,Tag:NLS(Unk)
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General Information
Symbol
Avic\GFPUAS.Tag:MCP,Tag:NLS(Unk)
Species
A. victoria
Name
FlyBase ID
FBal0340429
Feature type
allele
Associated gene
Avic\GFP
Associated Insertion(s)
Carried in Construct
P{UAS-MCP.GFP.nls}
Also Known As
UAS-GFP-MS2-nls
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(van Gemert et al., 2009)
Progenitor genotype
Carried in construct
P{UAS-MCP.GFP.nls}
Cytology
Description

UASt regulatory sequences drive expression of GFP tagged with Tag:MCP and with a nuclear localization sequence (Tag:NLS(Unk)). In the presence of a mRNA tagged with Tag:MS2 (an RNA stem loop to which Tag:MCP binds), the fusion protein can bind to this tagged mRNA, allowing its localization within the cell to be studied. In the absence of a Tag:MS2-tagged mRNA (or when unbound), the GFP-Tag:MCP fusion protein will be targeted to the nucleus due to the presence of the Tag:NLS(Unk) tag.

(van Gemert et al., 2009)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
GFP
Tagged with
Tag:MCP
Tag:NLS(Unk)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (5)
      Reported As
      Symbol Synonym
      Avic\GFPUAS.Tag:MCP,Tag:NLS(Unk)
      Avic\GFPUAS.Tag:MS2-CP,Tag:NLS(Unk)
      MS2\MCPScer\UAS.T:Avic\GFP,T:Uuuu\nls-Unk
      MS2\MCPScer\UAS.T:Avic\GFP,T:Zzzz\nls-KKKRKV
      MS2\MCPScer\UAS.T:Avic\GFP,T:Zzzz\nls1
      Name Synonyms
      Secondary FlyBase IDs
      • FBal0285842
      • FBal0340397
      References (3)