The first exon of Setd3 ( X:6967564..6968737 ), including its translation start site and approximately half of the coding sequence, has been removed and replaced with a dsRED expression cassette. (Although this region includes the terminal part of the annotated 3'UTR of CG14431, expression of CG14431 is unaffected.)
The first exon of Setd3 ( X:6967564..6968737 ), including its translation start site and approximately half of the coding sequence, has been removed and replaced with a dsRED expression cassette.
Setd3KO homozygotes do not show any obvious defects in patterning, wing size, body weight, locomotor activity (i.e. in climbing capacity), female fertility or developmental time until pupation, as compared to controls.
