FlyBase Allele Report: Hsap\GULP1[UAS.cVCa]

General Information

Symbol

Hsap\GULP1^UAS.cVCa

Species

H. sapiens

Name

UAS construct a of Vivien Chiu

FlyBase ID

FBal0342456

Feature type

allele

Associated gene

Hsap\GULP1

Associated Insertion(s)

Carried in Construct

P{UAS-hGULP1.VC}

Key Links

Transgenic product class

cDNA

(Vivien Chiu et al., 2017)

wild_type

(Vivien Chiu et al., 2017)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

cDNA

(Vivien Chiu et al., 2017)

wild_type

(Vivien Chiu et al., 2017)

Mutagen

in vitro construct

(Vivien Chiu et al., 2017)

Progenitor genotype

Carried in construct

P{UAS-hGULP1.VC}

Cytology

Description

UASt regulates expression of the full length human Hsap\GULP1 cDNA.

(Vivien Chiu et al., 2017)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

Hsap\GULP1

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 1 )

Disease

Interaction

References

ameliorates Alzheimer's disease

modeled by Hsap\APP^695.UAS.Exel, Hsap\BACE1^UAS.Exel

(Vivien Chiu et al., 2017)

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

The expression of Hsap\GULP1^UAS.cVCa under the control of Scer\GAL4^GMR.PF does not significantly affect the number of rhabdomeres per ommatidium.

(Vivien Chiu et al., 2017)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

Hsap\GULP1^UAS.cVCa, Scer\GAL4^elav-C155 is a suppressor of abnormal locomotor behavior | adult stage phenotype of Hsap\APP^695.UAS.Exel, Hsap\BACE1^UAS.Exel, Scer\GAL4^elav-C155

(Vivien Chiu et al., 2017)

Hsap\GULP1^UAS.cVCa, Scer\GAL4^elav-C155 is a suppressor of short lived phenotype of Hsap\APP^695.UAS.Exel, Hsap\BACE1^UAS.Exel, Scer\GAL4^elav-C155

(Vivien Chiu et al., 2017)

Hsap\GULP1^UAS.cVCa, Scer\GAL4^GMR.PF is a suppressor of decreased cell number | adult stage phenotype of Hsap\APP^695.UAS.Exel, Hsap\BACE1^UAS.Exel, Scer\GAL4^GMR.PF

(Vivien Chiu et al., 2017)

Phenotype Manifest In

Suppressor of

Statement

Reference

Hsap\GULP1^UAS.cVCa, Scer\GAL4^GMR.PF is a suppressor of ommatidium phenotype of Hsap\APP^695.UAS.Exel, Hsap\BACE1^UAS.Exel, Scer\GAL4^GMR.PF

(Vivien Chiu et al., 2017)

Hsap\GULP1^UAS.cVCa, Scer\GAL4^GMR.PF is a suppressor of rhabdomere phenotype of Hsap\APP^695.UAS.Exel, Hsap\BACE1^UAS.Exel, Scer\GAL4^GMR.PF

(Vivien Chiu et al., 2017)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Hsap\GULP1^UAS.cVCa

Name Synonyms

UAS construct a of Vivien Chiu

Secondary FlyBase IDs

References (1)

Report Sections

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