FlyBase Allele Report: Hsap\PLA2G6[UAS.cLa]

FB2026_01 , released March 12, 2026

FB2026_01 , released March 12, 2026

Allele: Hsap\PLA2G6^UAS.cLa

General Information

Symbol

Hsap\PLA2G6^UAS.cLa

Species

H. sapiens

Name

UAS construct of Lin

FlyBase ID

FBal0343302

Feature type

allele

Associated gene

Associated Insertion(s)

Carried in Construct

PBac{UAS-hPLA2G6.L}

Key Links

Transgenic product class

(Lin et al., 2018)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

(Lin et al., 2018)

Mutagen

in vitro construct

(Lin et al., 2018)

Progenitor genotype

Carried in construct

PBac{UAS-hPLA2G6.L}

Cytology

Description

UASt regulatory sequences drive expression of wild-type Hsap\PLA2G6 (sequence derived from the MGC:45156 clone).

(Lin et al., 2018)

Allele components

Component

Use(s)

Regulatory region(s)

binary expression system - regulatory region

Encoded product / tool

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 1 )

Disease

Interaction

References

ameliorates Parkinson's disease 14

modeled by iPLA2-VIA^Δ174

(Lin et al., 2018)

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

Scer\GAL4^Act5C.PI/Hsap\PLA2G6^UAS.cLa is a suppressor | partially of bang sensitive phenotype of iPLA2-VIA^Δ174

(Lin et al., 2018)

Scer\GAL4^elav-C155/Hsap\PLA2G6^UAS.cLa is a suppressor | partially of bang sensitive phenotype of iPLA2-VIA^Δ174

(Lin et al., 2018)

Scer\GAL4^Act5C.PI/Hsap\PLA2G6^UAS.cLa is a suppressor | partially of short lived phenotype of iPLA2-VIA^Δ174

(Lin et al., 2018)

Scer\GAL4^elav-C155/Hsap\PLA2G6^UAS.cLa is a suppressor of abnormal neurophysiology | adult stage | progressive phenotype of iPLA2-VIA^Δ174

(Lin et al., 2018)

Scer\GAL4^Act5C.PI/Hsap\PLA2G6^UAS.cLa is a suppressor of abnormal neurophysiology | adult stage | progressive phenotype of iPLA2-VIA^Δ174

(Lin et al., 2018)

NOT Suppressor of

Statement

Reference

Scer\GAL4^elav-C155/Hsap\PLA2G6^UAS.cLa is a non-suppressor of short lived phenotype of iPLA2-VIA^Δ174

(Lin et al., 2018)

Phenotype Manifest In

Suppressor of

Statement

Reference

Scer\GAL4^elav-C155/Hsap\PLA2G6^UAS.cLa is a suppressor of retina | progressive phenotype of iPLA2-VIA^Δ174

(Lin et al., 2018)

Scer\GAL4^Act5C.PI/Hsap\PLA2G6^UAS.cLa is a suppressor of retina | progressive phenotype of iPLA2-VIA^Δ174

(Lin et al., 2018)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

80137

y¹ w^*; PBac{UAS-hPLA2G6.L}VK00037; MKRS/TM6B, Tb¹

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Hsap\PLA2G6^UAS.cLa

Name Synonyms

UAS construct of Lin

Secondary FlyBase IDs

References (1)

Report Sections