FB2026_02 , released June 18, 2026
Allele: Drer\ltkUAS.cFa
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General Information
Symbol
Drer\ltkUAS.cFa
Species
D. rerio
Name
FlyBase ID
FBal0343649
Feature type
allele
Associated gene
Drer\ltk
Associated Insertion(s)
Carried in Construct
P{UAS-ltk.F}
Transgenic product class
wild_type
(Fadeev et al., 2018)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Fadeev et al., 2018)
Mutagen
in vitro construct
(Fadeev et al., 2018)
Progenitor genotype
Carried in construct
P{UAS-ltk.F}
Cytology
Description

UAS regulatory sequences drive expression of Drer\ltk.

(Fadeev et al., 2018)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Drer\ltk
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 1 )
      Disease
      Evidence
      References
      DOES NOT model  neuroblastoma
      CEA
      (Fadeev et al., 2018)
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expressing Drer\ltkUAS.cFa under the control of Scer\GAL4GMR.PF has no impact on eye phenotype.

      (Fadeev et al., 2018)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Co-expressing Drer\ltkUAS.cFa and Drer\alkal1UAS.cFa, Drer\alkal2aUAS.cFa or Drer\alkal2bUAS.cFa under the control of Scer\GAL4GMR.PF results in a rough eye phenotype.

      (Fadeev et al., 2018)
      Xenogenetic Interactions
      Statement
      Reference

      Co-expressing Drer\ltkUAS.cFa and either Hsap\ALKAL1UAS.cGa or Hsap\ALKAL2UAS.cGa under the control of Scer\GAL4GMR.PF results in a rough eye phenotype when flies are raised at 18[o]C. A rearing temperature of 25[o]C kills the flies.

      (Fadeev et al., 2018)
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Drer\ltkUAS.cFa
      Name Synonyms
      Secondary FlyBase IDs
        References (1)