FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
Allele: Dmel\Ca-Ma2dex1
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General Information
Symbol
Dmel\Ca-Ma2dex1
Species
D. melanogaster
Name
FlyBase ID
FBal0343969
Feature type
allele
Associated gene
Dmel\Ca-Ma2d
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Reuveny et al., 2018)
Progenitor genotype
P{EPgy2}Ca-Ma2dEY09750
(Reuveny et al., 2018)
Cytology
Description

Imprecise excision of the P{EPgy2}CG42817EY09750 insertion resulting deletion and rearrangement within the first intron, 5' to the inserted element, extending to the end of the first exon.

(Reuveny et al., 2018)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
complex_substitution
2L:16,232,255..16,234,992 [+]
Comment:

Inferred boundaries of an imprecise excision/rearrangement event in the first intron of Ca-Ma2d extending from 21 bases from the end of the first exon to the site of the P{EPgy2}CG42817EY09750 insertion.

(Reuveny et al., 2018)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Ca-Ma2dex1/Df(2L)BSC293 transheterozygous larvae show a significantly decreased crawling speed, as compared to controls; their muscles show abnormal nuclear positioning where the myonuclei are significantly closer to each other and often create small aggregates, despite of similar muscle size.

      (Reuveny et al., 2018)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Ca-Ma2dex1
      Name Synonyms
      Secondary FlyBase IDs
        References (1)