FlyBase Allele Report: Hsap\KCNJ2[lexAop.cHa]

FB2026_01 , released March 12, 2026

FB2026_01 , released March 12, 2026

Allele: Hsap\KCNJ2^lexAop.cHa

General Information

Symbol

Hsap\KCNJ2^lexAop.cHa

Species

H. sapiens

Name

FlyBase ID

FBal0344511

Feature type

allele

Associated gene

Associated Insertion(s)

Carried in Construct

P{lexAop-Kir2.1.H}

Also Known As

lexAop-Kir2.1

Key Links

Transgenic product class

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

Mutagen

in vitro construct

(Hu et al., 2017)

Progenitor genotype

Carried in construct

P{lexAop-Kir2.1.H}

Cytology

Description

lexAop regulatory sequences drive expression of Kir2.1.

(Hu et al., 2017)

Allele components

Component

Use(s)

Regulatory region(s)

binary expression system - regulatory region

Encoded product / tool

neuron inhibition tool

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal oviposition, with Ecol\lexA^VP16.Gr5a

(Wu et al., 2019)

abnormal oviposition, with Ecol\lexA^VP16.Gr64f

(Wu et al., 2019)

abnormal pain response | larval stage, with Ecol\lexA^p65.Ilp7.DP

(Hu et al., 2017)

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhancer of

Statement

Reference

Ecol\lexA^GMR27H06/Hsap\KCNJ2^lexAop.cHa is a non-enhancer of abnormal locomotor behavior | larval stage | conditional phenotype of Cnoc\ChR1::Csub\ChR^{CsChrimson.IVS.20xUAS.Venus}, Scer\GAL4^GMR82E12

(Hu et al., 2017)

Ecol\lexA^p65.Ilp7.DP/Hsap\KCNJ2^lexAop.cHa is a non-enhancer of abnormal locomotor behavior | larval stage | conditional phenotype of Cnoc\ChR1::Csub\ChR^{CsChrimson.IVS.20xUAS.Venus}, Scer\GAL4^GMR82E12

(Hu et al., 2017)

NOT Suppressor of

Statement

Reference

Ecol\lexA^GMR27H06/Hsap\KCNJ2^lexAop.cHa is a non-suppressor of abnormal locomotor behavior | larval stage | conditional phenotype of Cnoc\ChR1::Csub\ChR^{CsChrimson.IVS.20xUAS.Venus}, Scer\GAL4^GMR82E12

(Hu et al., 2017)

Ecol\lexA^p65.Ilp7.DP/Hsap\KCNJ2^lexAop.cHa is a non-suppressor of abnormal locomotor behavior | larval stage | conditional phenotype of Cnoc\ChR1::Csub\ChR^{CsChrimson.IVS.20xUAS.Venus}, Scer\GAL4^GMR82E12

(Hu et al., 2017)

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Hsap\KCNJ2^lexAop.cHa

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections