FlyBase Experimental Tool Report: Kir2.1

FB2026_02 , released June 18, 2026

FB2026_02 , released June 18, 2026

Experimental tool: Kir2.1

General Information

Symbol

Kir2.1

FlyBase ID

FBto0000566

Name

Description

Description

Kir2.1 corresponds to the inwardly rectifying potassium channel encoded by the Homo sapiens KCNJ2 gene (HGNC:6263). It can be used to produce membrane hyperpolarization and inhibit neuron activity (PMID:10024355, FBrf0134721).

Uses

neuron inhibition tool

External Crossreferences and Linkouts

Related experimental tools

Transgenic Constructs

Encodes tool (37)

Transgenic construct(s)

Component allele

Reg. region

Encoded product / tool

Tagged with

Also carries

Stocks

P{UAS-Hsap\KCNJ2.EGFP}

Hsap\KCNJ2^UAS.EGFP

UASt

Kir2.1: neuron inhibition tool

EGFP: green fluorescent protein

Hsap\KCNJ2^{20XUAS.mCyRFP3}

UAS

Kir2.1: neuron inhibition tool

mCyRFP3: red fluorescent protein

PBac{13XlexAop-IVS-mCyRFP3::Kir2.1}

Hsap\KCNJ2^{13XlexAop.mCyRFP3}

lexAop

Kir2.1: neuron inhibition tool

mCyRFP3: red fluorescent protein

P{QUAS-Kir2.1.P}

Hsap\KCNJ2^QUAS.cPa

QUAS

Kir2.1: neuron inhibition tool

P{UAS(FRT.stop)Hsap\KCNJ2}

Hsap\KCNJ2^FRT.stop.UAS

UAS

Kir2.1: neuron inhibition tool

FRT: recombinase target site

P{10xUAS(FRT.EGFP::Kir2.1-stop)mCh}

Hsap\KCNJ2^{10xUAS.EGFP.FLP-OFF}

UAS

Kir2.1: neuron inhibition tool

EGFP: green fluorescent protein

FRT: recombinase target site

P{10xUAS(FRT.mCh-stop)EGFP::Kir2.1}

Hsap\KCNJ2^{10xUAS.EGFP.FLP-ON}

UAS

Kir2.1: neuron inhibition tool

EGFP: green fluorescent protein

FRT: recombinase target site

Hsap\KCNJ2^{FRT.STOP.10x.UAS.GFP}

UAS

Kir2.1: neuron inhibition tool

GFP: green fluorescent protein

FRT: recombinase target site

Hsap\KCNJ2^10x.UAS.GFP

UAS

Kir2.1: neuron inhibition tool

GFP: green fluorescent protein

FRT: recombinase target site

Hsap\KCNJ2^{IVS.10xUAS.EGFP}

UAS

Kir2.1: neuron inhibition tool

EGFP: green fluorescent protein

P{13xlexAop2(FRT.myr::tdTomato-SV40)EGFP::Kir2.1}

Hsap\KCNJ2^{13xlexAop.FRT.JFRC58.EGFP}

lexAop

Kir2.1: neuron inhibition tool

EGFP: green fluorescent protein

FRT: recombinase target site

P{13xlexAop2-hKCNJ2.EGFP}

Hsap\KCNJ2^{13xlexAop2.EGFP}

lexAop

Kir2.1: neuron inhibition tool

EGFP: green fluorescent protein

P{13xlexAop-Kir2.1.Z}

Hsap\KCNJ2^{13xlexAop.cZa}

lexAop

Kir2.1: neuron inhibition tool

P{Cre80-Kir2.1}

Hsap\KCNJ2^UAS.cLa.EGFP

UAS

Kir2.1: neuron inhibition tool

EGFP: green fluorescent protein

P{lexAop-EGFP-Kir2.1}

Hsap\KCNJ2^lexAop.EGFP

lexAop

Kir2.1: neuron inhibition tool

EGFP: green fluorescent protein

P{lexAop-Kir2.1.EGFP.U}

Hsap\KCNJ2^{lexAop.cUa.GFP}

lexAop

Kir2.1: neuron inhibition tool

GFP: green fluorescent protein

P{lexAop-Kir2.1.F}

Hsap\KCNJ2^lexAop.cFa

lexAop

Kir2.1: neuron inhibition tool

P{lexAop-Kir2.1.H}

Hsap\KCNJ2^lexAop.cHa

lexAop

Kir2.1: neuron inhibition tool

P{lexAop-Kir2.1.U}

Hsap\KCNJ2^lexAop.cUa

lexAop

Kir2.1: neuron inhibition tool

P{UAS(FRT.CD2)Kir2.1-GFP}

Hsap\KCNJ2^FRT.UAS.GFP

UASt

Kir2.1: neuron inhibition tool

GFP: green fluorescent protein

FRT: recombinase target site

P{UAS(FRT.Stop)Kir2.1-EGFP}

Hsap\KCNJ2^{FRT.Stop.UAS.EGFP}

UAS

Kir2.1: neuron inhibition tool

EGFP: green fluorescent protein

FRT: recombinase target site

P{UAS(-FRT)Kir2.1-EGFP}

Hsap\KCNJ2^UAS.EGFP.cDa

UAS

Kir2.1: neuron inhibition tool

EGFP: green fluorescent protein

P{UAS(-FRT)Kir2.1-GFP}

Hsap\KCNJ2^UAS.GFP

UASt

Kir2.1: neuron inhibition tool

GFP: green fluorescent protein

FRT: recombinase target site

P{UAS-EGFP-Kir2.1.F}

Hsap\KCNJ2^UAS.EGFP.cFa

UAS

Kir2.1: neuron inhibition tool

EGFP: green fluorescent protein

P{UAS-hKCNJ2.U}

Hsap\KCNJ2^UAS.cUa

UAS

Kir2.1: neuron inhibition tool

P{UAS-Kir2.1.B}

Hsap\KCNJ2^UAS.cBa

UAS

Kir2.1: neuron inhibition tool

P{UAS-Kir2.1.EGFP.H}

Hsap\KCNJ2^UAS.cHa.EGFP

UAS

Kir2.1: neuron inhibition tool

EGFP: green fluorescent protein

P{UAS-Kir2.1.EGFP.U}

Hsap\KCNJ2^UAS.cUa.EGFP

UAS

Kir2.1: neuron inhibition tool

EGFP: green fluorescent protein

P{UAS-Kir2.1.GFP.U}

Hsap\KCNJ2^UAS.cUa.GFP

UAS

Kir2.1: neuron inhibition tool

GFP: green fluorescent protein

P{UAS-Kir2.1.Z}

Hsap\KCNJ2^UAS.cZa

UASt

Kir2.1: neuron inhibition tool

P{UAS-Kir2.1E.Syn21}

Hsap\KCNJ2^E.UAS.Syn21

UAS

Kir2.1: neuron inhibition tool

P{UAS-Kir2.1-T2A-myr::tdTOM-3xHA}

Hsap\KCNJ2^{UAS.T2A-myr::tdTOM-3xHA}

UAS

Kir2.1: neuron inhibition tool

PBac{5XUAS-Kir2.1.EGFP}

Hsap\KCNJ2^5XUAS.EGFP

UAS

Kir2.1: neuron inhibition tool

EGFP: green fluorescent protein

PBac{13xlexAop2-IVS-hKCNJ2.EGFP}

Hsap\KCNJ2^{IVS.13xlexAop2.EGFP}

lexAop

Kir2.1: neuron inhibition tool

EGFP: green fluorescent protein

PBac{20xUAS(FRT.tdTomato::Kir2.1)mCD8::GFP}

Hsap\KCNJ2^{20xUAS.FRT.tdTomato}

UAS

Kir2.1: neuron inhibition tool

tdTomato: red fluorescent protein

FRT: recombinase target site

PBac{UAS-EGFP-Kir2.1.D}

Hsap\KCNJ2^UAS.cDa.EGFP

UAS

Kir2.1: neuron inhibition tool

EGFP: green fluorescent protein

PBac{UAS-Kir2.1.C}

Hsap\KCNJ2^UAS.cCa

UAS

Kir2.1: neuron inhibition tool

Insertions ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Kir2.1

Name Synonyms

Secondary FlyBase IDs

References (31)

Report Sections