FlyBase Allele Report: Dmel\Not3[UAS.cVa]

FB2026_01 , released March 12, 2026

FB2026_01 , released March 12, 2026

Allele: Dmel\Not3^UAS.cVa

General Information

Symbol

Dmel\Not3^UAS.cVa

Species

D. melanogaster

Name

UAS construct a of Vicente

FlyBase ID

FBal0344652

Feature type

allele

Associated gene

Associated Insertion(s)

Carried in Construct

PBac{UAS-Not3.V}

Key Links

Transgenic product class

(Vicente et al., 2018)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

(Vicente et al., 2018)

Mutagen

in vitro construct

(Vicente et al., 2018)

Progenitor genotype

Carried in construct

PBac{UAS-Not3.V}

Cytology

Description

UASt regulatory sequences drive expression of wild-type Not3.

(Vicente et al., 2018)

Allele components

Component

Use(s)

Regulatory region(s)

binary expression system - regulatory region

Encoded product / tool

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 1 )

Disease

Interaction

References

ameliorates cancer

modeled by lola^GS88A8, psq^GS88A8

(Vicente et al., 2018)

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

Not3^UAS.cVa, Scer\GAL4^ey.PH is a suppressor of neoplasia | adult stage phenotype of Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8

(Vicente et al., 2018)

Not3^UAS.cVa, Scer\GAL4^ey.PH is a suppressor of increased occurrence of cell division | larval stage phenotype of Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8

(Vicente et al., 2018)

Not3^UAS.cVa, Scer\GAL4^ey.PH is a suppressor of visible | adult stage phenotype of Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8

(Vicente et al., 2018)

NOT Suppressor of

Statement

Reference

Not3^UAS.cVa, Scer\GAL4^ey.PH is a non-suppressor of increased cell death | larval stage phenotype of Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8

(Vicente et al., 2018)

Phenotype Manifest In

Suppressor of

Statement

Reference

Not3^UAS.cVa, Scer\GAL4^ey.PH is a suppressor of eye phenotype of Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8

(Vicente et al., 2018)

Not3^UAS.cVa, Scer\GAL4^ey.PH is a suppressor of eye disc phenotype of Delta^UAS.cDa, Scer\GAL4^ey.PH, lola^GS88A8, psq^GS88A8

(Vicente et al., 2018)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Partially rescues

Not3^UAS.cVa/Scer\GAL4^ey.PH partially rescues Not3^KK102144

(Vicente et al., 2018)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Not3^UAS.cVa

Name Synonyms

UAS construct a of Vicente

Secondary FlyBase IDs

References (1)

Report Sections