FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
Allele: Dmel\AP-1-2βΔ1
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General Information
Symbol
Dmel\AP-1-2βΔ1
Species
D. melanogaster
Name
FlyBase ID
FBal0344769
Feature type
allele
Associated gene
Dmel\AP-1-2β
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
Delta2-3 transposase
(Zong et al., 2018)
Progenitor genotype
P{EPgy2}EY01200
(Zong et al., 2018)
Cytology
Description

1381bp deletion that removes a small C-terminal part of the coding region (amino acids 861-921) and the entire 3'UTR.

(Zong et al., 2018)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
deletion
X:19,734,046..19,735,426 [+]
Comment:

Inferred boundaries of a 1381bp deletion resulting from the imprecise excision of P{EPgy2}EY01200 that removes the 3' end of AP-1-2beta starting in codon 861, the 3' UTR, and most of the intergenic region between AP-1-2beta and CG14234.

(Zong et al., 2018)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      AP-1-2βΔ1 homozygous ddaC neurons within mosaic individuals present mild but fully penetrant dendrite pruning defects at 16h after puparium formation, as compared to controls.

      (Zong et al., 2018)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      AP-1-2βΔ1
      BapΔ1
      (Zong et al., 2018)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)