FlyBase Allele Report: Gthe\ACR1[UAS.d.EYFP]

General Information

Symbol

Gthe\ACR1^UAS.d.EYFP

Species

G. theta

Name

FlyBase ID

FBal0344776

Feature type

allele

Associated gene

Gthe\ACR1

Associated Insertion(s)

Carried in Construct

P{UAS-GtACR1.d.EYFP}

Also Known As

UAS-GtACR1, UAS-gtACR1-eYFP, UAS-GtACR, UAS-GtACR1-YFP, UAS-GtACR1::eYFP, 20XUAS-GtACR1, GtACR1, 20X-UAS-GtACR1::EYFP, UAS-GtACR1.d.EYFP

Transgenic product class

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

Mutagen

in vitro construct

(Mohammad et al., 2017)

Progenitor genotype

Carried in construct

P{UAS-GtACR1.d.EYFP}

Cytology

Description

UAS regulatory sequences drive expression of a Drosophila codon-optimized version of GtACR1 that is tagged with EYFP.

(Mohammad et al., 2017)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

GtACR1

light-regulated neuron inhibition tool

Tagged with

EYFP

yellow fluorescent protein

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal chemosensory behavior | larval stage, with Scer\GAL4^ppk.PG

(Kim et al., 2020)

abnormal courtship behavior | male, with Scer\GAL4^Ir52a.PK

(He et al., 2019)

abnormal larval locomotory behavior | light conditional | chemical conditional, with Scer\GAL4^GMR82E12

(Zhou et al., 2025)

abnormal locomotor behavior | adult stage | conditional, with Scer\GAL4^0273-G4

(Stern et al., 2019)

abnormal mating behavior | female, with Scer\GAL4^Ir52a.PK

(He et al., 2019)

abnormal mating behavior | male, with Scer\GAL4^Ir52a.PK

(He et al., 2019)

abnormal pain response | larval stage, with Scer\GAL4^ppk.PG

(Kim et al., 2020)

abnormal sensory perception | larval stage, with Scer\GAL4^ppk.PG

(Kim et al., 2020)

abnormal sleep | adult stage | conditional, with Scer\GAL4^GMR18H11

(Guo et al., 2018)

abnormal sleep | adult stage | conditional, with Scer\GAL4^GMR67F03

(Guo et al., 2018)

abnormal stress response | adult stage | conditional, with Scer\GAL4^VT038828

(Guo et al., 2018)

decreased efficacy of long-term memory | adult stage, with Scer\GAL4^GMR58E02

(Jacob and Waddell, 2020)

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

Gthe\ACR1^UAS.d.EYFP, Scer\GAL4^VT038828 has abnormal stress response | adult stage | conditional phenotype, suppressible by Cnoc\ChR1::Csub\ChR^{CsChrimson.IVS.13XLexAop2.Venus}/Ecol\lexA^GMR18H11

(Guo et al., 2018)

NOT Enhancer of

Statement

Reference

Scer\GAL4^VT038828/Gthe\ACR1^UAS.d.EYFP is a non-enhancer of decreased rate of movement | adult stage | conditional phenotype of Cnoc\ChR1::Csub\ChR^{CsChrimson.IVS.13XLexAop2.Venus}, Ecol\lexA^GMR18H11

(Guo et al., 2018)

Suppressor of

Statement

Reference

Scer\GAL4^VT038828/Gthe\ACR1^UAS.d.EYFP is a suppressor | partially of abnormal sleep | adult stage | conditional phenotype of Cnoc\ChR1::Csub\ChR^{CsChrimson.IVS.13XLexAop2.Venus}, Ecol\lexA^GMR18H11

(Guo et al., 2018)

Scer\GAL4^VT038828/Gthe\ACR1^UAS.d.EYFP is a suppressor of abnormal stress response | adult stage | conditional phenotype of Cnoc\ChR1::Csub\ChR^{CsChrimson.IVS.13XLexAop2.Venus}, Ecol\lexA^GMR18H11

(Guo et al., 2018)

NOT Suppressor of

Statement

Reference

Scer\GAL4^VT038828/Gthe\ACR1^UAS.d.EYFP is a non-suppressor of decreased rate of movement | adult stage | conditional phenotype of Cnoc\ChR1::Csub\ChR^{CsChrimson.IVS.13XLexAop2.Venus}, Ecol\lexA^GMR18H11

(Guo et al., 2018)

Other

Statement

Reference

Gthe\ACR1^UAS.d.EYFP, Hsap\RELA^AD.R31C03, Scer\GAL4^DBD.Tdc2 has decreased rate of larval locomotory behavior | light conditional phenotype

(Bakshinska et al., 2025)

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (2)

Bloomington

92983

w^*; P{UAS-GtACR1.d.EYFP}attP2

92988

w^*; P{UAS-GtACR1.d.EYFP}attP40/CyO

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Gthe\ACR1^UAS.d.EYFP

Name Synonyms

Secondary FlyBase IDs

References (79)

Report Sections

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