FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\αTub84BTuba1a-tail
Open Close
General Information
Symbol
Dmel\αTub84BTuba1a-tail
Species
D. melanogaster
Name
FlyBase ID
FBal0345030
Feature type
allele
Associated gene
Dmel\αTub84B
Associated Insertion(s)
TI{TI}αTub84BTuba1a-tail
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
phiC31 integrase
(Jenkins et al., 2017)
Progenitor genotype
αTub84BKO-attP
(Jenkins et al., 2017)
Associated Insertion(s)
TI{TI}αTub84BTuba1a-tail
Cytology
Description

αTub84B sequence in which the C-terminal tail has been replaced by the equivalent sequence from a vertebrate ortholog has been knocked in to the attP site present in the αTub84BKO-attP knockout line.

(Jenkins et al., 2017)
Allele components
Component
Use(s)
Also carries
loxP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
delins
3R:7,088,551..7,088,580 [+]
Inserted_sequence:

ACGGCGAGGGTGAGGAAGAAGGAGAGGAGTACTAA

Comment:

The endogenous C-terminal tail sequence, DGEGEGAEEY, was replaced by DGEGEEEGEEY, which corresponds to the C-terminal tail of human TUBA1A, the homolog of alphaTub84B. The replacement DNA sequence is: 5'-ACGGCGAGGGTGAGGAAGAAGGAGAGGAGTACTAA-3'.

(Wildonger, 2019.6.18)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      αTub84BTuba1a-tail
      (Jenkins et al., 2017)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)