FB2026_02 , released June 18, 2026
Allele: Dmel\EgfrlexAVP16
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General Information
Symbol
Dmel\EgfrlexAVP16
Species
D. melanogaster
Name
FlyBase ID
FBal0345042
Feature type
allele
Associated gene
Dmel\Egfr
Associated Insertion(s)
TI{TI}EgfrlexAVP16
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
CRISPR/Cas9
(Courgeon et al., 2018)
gene targeting by homologous recombination
(Courgeon et al., 2018)
Progenitor genotype
Associated Insertion(s)
TI{TI}EgfrlexAVP16
Cytology
Description

lexA::VP16 coding sequence has been inserted at the C-terminal end of the endogenous Egfr coding sequence. The native Egfr 3'UTR is present downstream of the lexA::VP16 sequence, followed by an attP site and a Disc\RFPDsRed(T1).3xP3.cHa marker that were inserted during the mutagenesis event. The chimeric Egfr ::lexA::VP16 protein does not detectably activate reporter expression.

(Courgeon et al., 2018)
Allele components
Component
Use(s)
Also carries
attP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Egfr-LexAVP16 CRISPR
      (Courgeon et al., 2018)
      EgfrlexAVP16
      Name Synonyms
      Secondary FlyBase IDs
        References (1)