FlyBase Allele Report: Dmel\tx[KO-mCherry]

General Information

Symbol

Dmel\tx^KO-mCherry

Species

D. melanogaster

Name

FlyBase ID

FBal0345146

Feature type

allele

Associated gene

Dmel\tx

Associated Insertion(s)

TI{mCherry}tx^KO-mCherry

Carried in Construct

Also Known As

dei^KO-mCherry

Key Links

Allele class

amorphic allele - molecular evidence

Mutagen

phiC31 integrase

Nature of the Allele

Allele class

amorphic allele - molecular evidence

(Varte et al., 2022)

Mutagen

phiC31 integrase

(Hassan et al., 2018)

Progenitor genotype

TI{GFP}tx^KO-GFP

(Hassan et al., 2018)

Associated Insertion(s)

TI{mCherry}tx^KO-mCherry

Cytology

Description

The Recombinase-Mediated Cassette Exchange (RMCE) cassette in the TI{GFP}tx^KO-GFP insertion has been replaced with a cassette containing mCherry, resulting in mCherry being expressed under the control of tx regulatory sequences.

(Hassan et al., 2018)

Allele components

Component

Use(s)

Inserted element

TI{mCherry}

promoter trap

Encoded product / tool

mCherry

red fluorescent protein

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal flight | adult stage (with tx¹)

(Varte et al., 2022)

abnormal flight | adult stage (with tx^ju-1)

(Varte et al., 2022)

abnormal flight | adult stage | recessive

(Varte et al., 2022)

visible | adult stage (with tx¹)

(Varte et al., 2022)

visible | adult stage (with tx^ju-1)

(Varte et al., 2022)

visible | adult stage | recessive

(Varte et al., 2022)

Phenotype Manifest In

direct flight muscle motor neuron | conditional

(Varte et al., 2022)

wing

(Varte et al., 2022)

wing (with tx¹)

(Varte et al., 2022)

wing (with tx^ju-1)

(Varte et al., 2022)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Fails to complement

tx^ju-1

(Varte et al., 2022)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

dei^KO-mCherry

(Avetisyan et al., 2021, Hassan et al., 2018)

taxi^KO

(Varte et al., 2022)

tx^KO-mCherry

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

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