FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\IBINUAS.cVa
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General Information
Symbol
Dmel\IBINUAS.cVa
Species
D. melanogaster
Name
UAS construct a of Valanne
FlyBase ID
FBal0345609
Feature type
allele
Associated gene
Dmel\IBIN
Associated Insertion(s)
Carried in Construct
P{UAS-IBIN.V}
Key Links
Transgenic product class
wild_type
(Valanne et al., 2019)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Valanne et al., 2019)
Mutagen
in vitro construct
(Valanne et al., 2019)
Progenitor genotype
Carried in construct
P{UAS-IBIN.V}
Cytology
Description

UASt regulates expression of the full-length lncRNA:IBIN gene.

(Valanne et al., 2019)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
IBIN
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      The expression of lncRNA:IBINUAS.cVa under the control of Scer\GAL4c564 leads to a significant increase in survival to combined M. luteus and E. faecalis bacterial infection, but does not affect lifespan in the absence of infection, as compared to controls. This expression does not significantly affect the numbers of hemocytes or lamellocytes in either infected or non-infected larvae, as compared to controls.

      Expression under the combined control of Scer\GAL4He.PZ and Scer\GAL4Hml.Δ induces a small but significant increase in the total number of larval hemocytes in the absence of infection, but not upon L. boulardi bacterial infection, as compared to controls. This change does not seem to be due to an effect in differentiation, as there are no significant changes in the number of lamellocytes in either infected or non-infected larvae. Also, there is no noticeable loss of sessile bands, as compared to controls.

      (Valanne et al., 2019)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      IBINUAS.cVa
      lncRNA:IBINUAS.cVa
      Name Synonyms
      UAS construct a of Valanne
      Secondary FlyBase IDs
        References (2)