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General Information
Symbol
Dmel\fzrUAS.cTa
Species
D. melanogaster
Name
UAS construct a of Taniguchi
FlyBase ID
FBal0346061
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UASt regulatory sequences drive expression of a s fzr cDNA (derived from the RE20929 clone).

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

The expression of fzrUAS.cTa only before the binucleation stage (i.e. expression under the combined control of Scer\GAL4NP5399 and Gal80[ts], and shift from the permissive 19[o]C temperature to the restrictive 29[o]C temperature only during 30h-60h after puparium formation) leads to significantly smaller male accessory gland lobes in the expanded state, as well as significantly lower mating-induced shrinkage rate and efficiency, as compared to control. These male accessory gland lobes also exhibit significantly fewer cells and significantly lower overall ploidy than controls; moreover, whereas control male accessory gland cells are typically binucleate octoploid cells (4N x 2), fzrUAS.cTa-expressing glands show a high proportion of tetraploid or octoploid single-nucleated cells (4N x 1 or 8Nx1). This seem to correlate with reduced ejection of seminal fluid, as there is a significant decrease in accessory gland proteins (i.e. Sp-GFP) being transferred during mating, as compared to controls. Males expressing fzrUAS.cTa induce lower egg laying in mated females 10-14 after mating, but not before or after that period.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
fzrUAS.cTa
Name Synonyms
UAS construct a of Taniguchi
Secondary FlyBase IDs
    References (1)