FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\en79.Δ1.5.Tag:HA
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General Information
Symbol
Dmel\en79.Δ1.5.Tag:HA
Species
D. melanogaster
Name
FlyBase ID
FBal0346389
Feature type
allele
Associated gene
Dmel\en
Associated Insertion(s)
Carried in Construct
P{HA-en.79.Δ1.5}
Key Links
Genomic Maps

Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(De et al., 2019)
Progenitor genotype
en79.Tag:HA
(De et al., 2019)
Carried in construct
P{HA-en.79.Δ1.5}
Cytology
Description

79kb genomic fragment containing the en locus (extends from within an inv intron to the 3' end of the tou gene). The en coding sequence is tagged with Tag:HA. 1.5kb containing the strong constitutive enPRE has been deleted.

(De et al., 2019)
Allele components
Component
Use(s)
Regulatory region(s)
en
Encoded product / tool
en
Tagged with
Tag:HA
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
rescue_region
2R:11,499,333..11,578,495 [-]
Comment:

79kb genomic fragment containing the en locus (extends from within an inv intron to the 3' end of the tou gene) inserted at other chromosome locations to form a Polycomb domain.

(De et al., 2019)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      en79.Δ1.5.Tag:HA inserted in attP40 leads to fertile flies, whereas if inserted in attP3 leads to infertile flies.

      Males and females bearing one or two en79.Δ1.5.Tag:HA copies at attP40 show abdomen defects, namely pigmentation defects, severely disrupted bristle pattern, and cuticle defects.

      (De et al., 2019)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressed by
      Phenotype Manifest In
      Suppressed by
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Males and females bearing one en79.Δ1.5.Tag:HA copy at attP40 show abdomen defects, namely pigmentation defects, severely disrupted bristle pattern, and cuticle defects. One copy of either P{PRE.D}attP40 or P{enPRE.s}attP40 in trans at attP40 largely restores the abdominal pigmentation and bristle patterns, although a defect in fusion of the cuticle at the midline in abdominal segments remains. One copy P{enPRE.s}attP40 at attP3, however, does not suppress any of the abdominal defects.

      (De et al., 2019)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      en79.Δ1.5.Tag:HA
      Name Synonyms
      Secondary FlyBase IDs
        References (1)