FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\ASPPFA-WK.Ubi-p63E.GFP
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General Information
Symbol
Dmel\ASPPFA-WK.Ubi-p63E.GFP
Species
D. melanogaster
Name
FlyBase ID
FBal0346836
Feature type
allele
Associated gene
Dmel\ASPP
Associated Insertion(s)
Carried in Construct
PBac{Ubi-p63E-ASPP.FA-WK.GFP}
Key Links
Transgenic product class
missense_variant
(Bertran et al., 2019)
Mutagen
Nature of the Allele
Transgenic product class
missense_variant
(Bertran et al., 2019)
Mutagen
in vitro construct
(Bertran et al., 2019)
Progenitor genotype
Carried in construct
PBac{Ubi-p63E-ASPP.FA-WK.GFP}
Cytology
Description

Ubi-p63E promoter sequences drive expression of ASPP in which the RVxF motif has been mutated from RVSF to RASA and which carries a W897K substitution in the SH3 domains. The protein is tagged at the N-terminal end with GFP.

(Bertran et al., 2019)
Allele components
Component
Use(s)
Regulatory region(s)
Ubi-p63E
Encoded product / tool
ASPP
Tagged with
GFP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhancer of
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      ASPPFA-WK.Ubi-p63E.GFP partially rescues ASPPd/ASPP8

      (Bertran et al., 2019)
      Comments

      ASPPFA-WK.Ubi-p63E.GFP partially rescues the increased numbers of inter-ommatidial cells and misplaced bristles in the pupal eye, as well as the enlarged wings and the duplicated scutellar bristles, observed in ASPPd/ASPP8 transheterozygotes.

      (Bertran et al., 2019)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      ASPPFA-WK.Ubi-p63E.GFP
      Name Synonyms
      Secondary FlyBase IDs
        References (1)