FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\HBS148
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General Information
Symbol
Dmel\HBS148
Species
D. melanogaster
Name
FlyBase ID
FBal0346869
Feature type
allele
Associated gene
Dmel\HBS1
Associated Insertion(s)
P{?SUPor-P}HBS148
Carried in Construct
Key Links
Allele class

hypomorphic allele - molecular evidence

Mutagen
Nature of the Allele
Allele class

hypomorphic allele - molecular evidence

(Li et al., 2019)
Mutagen
Delta2-3 transposase
(Li et al., 2019)
Progenitor genotype
P{EPgy2}HBS1EY09557
(Li et al., 2019)
Associated Insertion(s)
P{?SUPor-P}HBS148
Cytology
Description

Imprecise excision of P{EPgy2}HBS1EY09557; 420bp of the original insertion remains.

(Li et al., 2019)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      HBS148 homozygous testis do not show any obvious germline cyst defects during early spermatogenesis, as they show the expected 1:1 nebenkern to nucleus ratio and the nebenkern and the nuclei have normal morphologies; there are defects in later spermatogenesis, as shown by individualization complex defects (significantly fewer individualization complexes and no intact individualization complex near the apical end of the testis), as compared to controls.

      (Li et al., 2019)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      HBS148
      Hbs148
      (Li et al., 2019)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)