FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Pect38K
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General Information
Symbol
Dmel\Pect38K
Species
D. melanogaster
Name
FlyBase ID
FBal0347226
Feature type
allele
Associated gene
Dmel\Pect
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Cytology
    Description

    Amino acid replacement: A247V.

    (Tsai et al., 2019)
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    point_mutation
    2L:13,209,721..13,209,721 [+]
    Nucleotide change:

    C13209721T

    Amino acid change:

    A247V | Pect-PB; A228V | Pect-PC; A235V | Pect-PD; A225V | Pect-PE

    Reported amino acid change:

    A247V

    Comment:

    Site of nucleotide substitution in mutant inferred by FlyBase curator based on reported amino acid change. Mutation location mapped relative to Pect-RB. That is the only Pect isoform that has an Ala at position 247.

    (Tsai et al., 2019)
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        At eclosion, Pect38K mutant photoreceptor cells in mosaic individuals show normal axon terminal morphology, as well as normal cell body morphology and arrangement in the retina; over the first 5 days of adult life, however, axon terminals develop irregular, swollen morphologies.

        (Tsai et al., 2019)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Additional Comments
        Genetic Interactions
        Statement
        Reference
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Rescued by

        Pect38K is rescued by PectUAS.cTa/Scer\GAL4GMR.PFa

        (Tsai et al., 2019)
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (2)
        Reported As
        Symbol Synonym
        Pect38K
        pect38K
        (Tsai et al., 2019)
        Name Synonyms
        Secondary FlyBase IDs
          References (1)