FlyBase Allele Report: Dmel\SA2[βTub85D.C.EGFP]

General Information

Symbol

Dmel\SA2^{βTub85D.C.EGFP}

Species

D. melanogaster

Name

FlyBase ID

FBal0350229

Feature type

allele

Associated gene

Dmel\SA2

Associated Insertion(s)

Carried in Construct

P{βTub85D-SA2-EGFP}

Key Links

Transgenic product class

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

Mutagen

in vitro construct

(Sun et al., 2019)

Progenitor genotype

Carried in construct

P{βTub85D-SA2-EGFP}

Cytology

Description

A 978bp fragment of βTub85D 5' regulatory sequence drives expression of SA-2, tagged at the C-terminal end with EGFP. A 477bp fragment from 3' of the βTub85D coding sequence is also present downstream of the EGFP coding sequence.

(Sun et al., 2019)

Allele components

Component

Use(s)

Regulatory region(s)

βTub85D

Encoded product / tool

SA2

Tagged with

EGFP

green fluorescent protein

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

SA2^{βTub85D.C.EGFP}, SA2^Z3-2138/SA2^Z3-0317 has abnormal meiotic cell cycle | spermatogenesis phenotype, suppressible | partially by mod(mdg4)^{βTub85D.mnm.C.EGFP}

(Sun et al., 2019)

Phenotype Manifest In

Suppressed by

Statement

Reference

SA2^{βTub85D.C.EGFP}, SA2^Z3-2138/SA2^Z3-0317 has sex chromosome | spermatogenesis phenotype, suppressible | partially by mod(mdg4)^{βTub85D.mnm.C.EGFP}

(Sun et al., 2019)

SA2^{βTub85D.C.EGFP}, SA2^Z3-2138/SA2^Z3-0317 has spermatocyte | spermatogenesis phenotype, suppressible | partially by mod(mdg4)^{βTub85D.mnm.C.EGFP}

(Sun et al., 2019)

SA2^{βTub85D.C.EGFP}, SA2^Z3-2138/SA2^Z3-0317 has testis | adult stage phenotype, suppressible | partially by mod(mdg4)^{βTub85D.mnm.C.EGFP}

(Sun et al., 2019)

NOT suppressed by

Statement

Reference

SA2^{βTub85D.C.EGFP}, SA2^Z3-2138/SA2^Z3-0317 has autosome | spermatogenesis phenotype, non-suppressible by mod(mdg4)^{βTub85D.mnm.C.EGFP}

(Sun et al., 2019)

SA2^{βTub85D.C.EGFP}, SA2^Z3-2138/SA2^Z3-0317 has nucleus | spermatogenesis phenotype, non-suppressible by mod(mdg4)^{βTub85D.mnm.C.EGFP}

(Sun et al., 2019)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Fails to rescue

SA2^{βTub85D.C.EGFP} fails to rescue SA2^Z3-2138/SA2^Z3-0317

(Sun et al., 2019)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

SA-2^{βTub85D.C.EGFP}

SA2^{βTub85D.C.EGFP}

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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