FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\AbiW452K.UAS.Tag:HA
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General Information
Symbol
Dmel\AbiW452K.UAS.Tag:HA
Species
D. melanogaster
Name
FlyBase ID
FBal0350336
Feature type
allele
Associated gene
Dmel\Abi
Associated Insertion(s)
Carried in Construct
P{UAS-Abi.W452K.HA}
Key Links
Transgenic product class
missense_variant
(Kim et al., 2019)
Mutagen
Nature of the Allele
Transgenic product class
missense_variant
(Kim et al., 2019)
Mutagen
in vitro construct
(Kim et al., 2019)
Progenitor genotype
Carried in construct
P{UAS-Abi.W452K.HA}
Cytology
Description

UASt regulatory sequences drive expression of the full-length Abi open reading frame (from the LD37010 cDNA clone), that has been mutated to carry the W452K amino acid replacement; this mutation is expected to result in a binding-defective protein. The coding sequence is tagged with Tag:HA.

(Kim et al., 2019)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Abi
Tagged with
Tag:HA
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Scer\GAL4elav-C155/AbiW452K.UAS.Tag:HA rescues Abi5/Df(3R)su(Hw)7

      (Kim et al., 2019)
      Comments

      Expressing AbiW452K.UAS.Tag:HA under the control of Scer\GAL4elav-C155 rescues the supernumerary phenotype of both mature and satellite boutons at the NMNJ in Abi5/Df(3R)su(Hw)7 third instar larvae.

      (Kim et al., 2019)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      AbiW452K.UAS.Tag:HA
      Name Synonyms
      Secondary FlyBase IDs
        References (1)