FB2026_03 , released September 17, 2026
Allele: Dmel\recDA
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General Information
Symbol
Dmel\recDA
Species
D. melanogaster
Name
FlyBase ID
FBal0350350
Feature type
allele
Associated gene
Dmel\rec
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
CRISPR/Cas9
(Hartmann et al., 2019)
gene targeting by homologous recombination
(Hartmann et al., 2019)
Progenitor genotype
Cytology
Description

Mutation of a conserved Asp residue in Walker motif B with an Ala residue; this mutation has been shown to destroy the ability to coordinate Mg[2+] for ATP hydrolysis in mini-chromosome maintenance proteins and other AAA+ ATPases.

(Hartmann et al., 2019)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
3R:15,831,008..15,831,008 [-]
Nucleotide change:

A15831008C

Amino acid change:

D537A | rec-PA; D537A | rec-PB

Reported amino acid change:

K?S

Comment:

Mutation of a conserved Asp residue in Walker motif B to an Ala residue. Site of nucleotide substitution in mutant inferred by FlyBase curator based on reported amino acid change.

(Hartmann et al., 2019)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
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      Disease
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      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
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      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      recDA
      (Hartmann et al., 2019)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)