FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\AxnKO
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General Information
Symbol
Dmel\AxnKO
Species
D. melanogaster
Name
FlyBase ID
FBal0351594
Feature type
allele
Associated gene
Dmel\Axn
Associated Insertion(s)
TI{TI}AxnKO
Carried in Construct
Key Links
Genomic Maps

Allele class

amorphic allele - molecular evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - molecular evidence

(Anvarian et al., 2016)
Mutagen
ends-out gene targeting
(Anvarian et al., 2016)
cre recombinase
(Anvarian et al., 2016)
FLPase
(Anvarian et al., 2016)
I-SceI
(Anvarian et al., 2016)
Progenitor genotype
Associated Insertion(s)
TI{TI}AxnKO
Cytology
Description

Deletion of the first three exons of Axn and replacement of this region with a cassette including an attP recombination site.

(Anvarian et al., 2016)
Allele components
Component
Use(s)
Also carries
attP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
delins
3R:30,030,936..30,032,102 [+]
Comment:

Deletion of the first three exons of Axn and replacement of this region with a cassette including an attP recombination site. Position of deletion endpoints on reference sequence determined from reported primer sequences.

(Anvarian et al., 2016)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      AxnKO wing disc clones are significantly larger than control clones, giving rise to tumor-like growths, and exhibit a round shape and a smooth edge instead of the jagged and elongated shape in controls.

      (Anvarian et al., 2016)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      AxnKO
      Axn[KO]
      (Anvarian et al., 2016)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)