FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Dh44-R2KO
Open Close
General Information
Symbol
Dmel\Dh44-R2KO
Species
D. melanogaster
Name
FlyBase ID
FBal0355605
Feature type
allele
Associated gene
Dmel\Dh44-R2
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class

amorphic allele - molecular evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - molecular evidence

(Yang et al., 2018)
Mutagen
CRISPR/Cas9
(Yang et al., 2018)
Progenitor genotype
Cytology
Description

Deletion of approximately 5.4 kb in Dh44-R2 locus ( 2R:12480822 to 12486265), including most of the exons.

(Yang et al., 2018)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
deletion
2R:12,480,822..12,486,265 [+]
Comment:

A 5444bp deletion that removes most of the coding region of Dh44-R2.

(Yang et al., 2018)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Dh44-R2KO homozygotes fail to show the increased food consumption induced by dietary amino acids normally observed in heterozygous and wild-type controls.

      (Yang et al., 2018)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      DH44-R2KO
      (Yang et al., 2018)
      Dh44-R2KO
      Name Synonyms
      Secondary FlyBase IDs
        References (1)