FlyBase Allele Report: Dmel\mt:Cyt-b[KSA2]

General Information

Symbol

Dmel\mt:Cyt-b^KSA2

Species

D. melanogaster

Name

FlyBase ID

FBal0356124

Feature type

allele

Associated gene

Dmel\mt:Cyt-b

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

natural population

Nature of the Allele

Allele class

Mutagen

natural population

(Salminen et al., 2019)

Progenitor genotype

Cytology

Description

Amino acid replacement: D21N.

(Salminen et al., 2019)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Other

Statement

Reference

mt:Cyt-b^KSA2, tko^25t has melanotic necrosis | pupal stage phenotype

(Salminen et al., 2019)

mt:Cyt-b^KSA2, tko^25t has melanotic necrosis | third instar larval stage phenotype

(Salminen et al., 2019)

mt:Cyt-b^KSA2, tko^25t has visible | pupal stage phenotype

(Salminen et al., 2019)

mt:Cyt-b^KSA2, tko^25t has increased cell number | third instar larval stage phenotype

(Salminen et al., 2019)

mt:Cyt-b^KSA2, tko^25t has lethal - all die before end of P-stage phenotype

(Salminen et al., 2019)

mt:Cyt-b^KSA2, tko^25t has visible | third instar larval stage phenotype

(Salminen et al., 2019)

mt:Cyt-b^KSA2, tko^25t has melanotic necrosis | pharate adult stage phenotype

(Salminen et al., 2019)

Phenotype Manifest In

Other

Statement

Reference

mt:Cyt-b^KSA2, tko^25t has embryonic/larval hemocyte | increased number | third instar larval stage phenotype

(Salminen et al., 2019)

mt:Cyt-b^KSA2, tko^25t has mitochondrial chromosome | increased number | pupal stage phenotype

(Salminen et al., 2019)

Additional Comments

Genetic Interactions

Statement

Reference

tko^25t in the mitochondrial (cybrid) background of Drosophila melanogaster strain (mt:Cyt-b^KSA2) leads to a significantly increased number of larval hemocytes; third instar larval, pupal and pharate adult melanotic nodules; and a significantly increased copy number of mitochondrial DNA in late pupae when compared to controls.

(Salminen et al., 2019)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

mt:Cyt-b^KSA2

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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