FlyBase Allele Report: Dmel\GluClα[MI02890-FlpStop.D]

General Information

Symbol

Dmel\GluClα^{MI02890-FlpStop.D}

Species

D. melanogaster

Name

FlyBase ID

FBal0356187

Feature type

allele

Associated gene

Dmel\GluClα

Associated Insertion(s)

Mi{FlpStop}GluClα^{MI02890-FlpStop.D}

Carried in Construct

Also Known As

GluClα^FlpStop.D

Key Links

Allele class

Mutagen

phiC31 integrase

Nature of the Allele

Allele class

Mutagen

phiC31 integrase

(Molina-Obando et al., 2019)

Progenitor genotype

Mi{MIC}GluClα^MI02890

(Molina-Obando et al., 2019)

Associated Insertion(s)

Mi{FlpStop}GluClα^{MI02890-FlpStop.D}

Cytology

Description

The RMCE cassette of the Mi{MIC}GluClα^MI02890 insertion has been replaced with a FlpStop cassette in 'disrupting' (D) orientation.

(Molina-Obando et al., 2019)

Allele components

Component

Use(s)

Inserted element

Mi{FlpStop}

gene trap

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

GluClα^{MI02890-FlpStop.D} is a suppressor of abnormal neurophysiology | larval stage phenotype of Scer\GAL4^VGlut1-OK371, VGlut1^UAS.cDa

(Li et al., 2021)

Phenotype Manifest In

Suppressor of

Statement

Reference

GluClα^{MI02890-FlpStop.D} is a suppressor of embryonic/larval neuromuscular junction phenotype of Scer\GAL4^VGlut1-OK371, VGlut1^UAS.cDa

(Li et al., 2021)

GluClα^{MI02890-FlpStop.D} is a suppressor of muscle cell of A1-7 ventral longitudinal muscle 3 | larval stage phenotype of Scer\GAL4^VGlut1-OK371, VGlut1^UAS.cDa

(Li et al., 2021)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

GluClα^FlpStop.D

(Li et al., 2021, Molina-Obando et al., 2019)

GluClα^{MI02890-FlpStop.D}

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

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