FB2026_02 , released June 18, 2026
Allele: Dmel\Or35aG54A
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General Information
Symbol
Dmel\Or35aG54A
Species
D. melanogaster
Name
FlyBase ID
FBal0356292
Feature type
allele
Associated gene
Dmel\Or35a
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
natural population
(Prieto-Godino et al., 2016)
Progenitor genotype
Cytology
Description

Nucleotide substitution resulting in a premature termination codon (PTC). This PTC shows read through; electrophysiological recordings of Or35a-expressing neurons in Or35aG54A flies shows a clear response when the neurons are presented with known agonists.

(Prieto-Godino et al., 2016)

Nucleotide substitution: G54A.

(Prieto-Godino et al., 2016)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
2L:15,623,505..15,623,505 [-]
Nucleotide change:

G15623505A

Reported nucleotide change:

G54A

Amino acid change:

W18term | Or35a-PB

Comment:

Nucleotide substitution resulting in a premature termination codon.

(Prieto-Godino et al., 2016)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Or35aG54A mutant ac3 sensilla in adults do not have any alterations in responses to octanol, compared to controls.

      (Prieto-Godino et al., 2016)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Or35aG54A
      Name Synonyms
      Secondary FlyBase IDs
        References (1)