FB2026_02 , released June 18, 2026
Allele: Dmel\ash1ΔBAH.Ubi-p63E
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General Information
Symbol
Dmel\ash1ΔBAH.Ubi-p63E
Species
D. melanogaster
Name
FlyBase ID
FBal0356961
Feature type
allele
Associated gene
Dmel\ash1
Associated Insertion(s)
Carried in Construct
M{Ubi-p63E-ash1.ΔBAH}
Key Links
Transgenic product class
inframe_deletion
(Dorafshan et al., 2019)
Mutagen
Nature of the Allele
Transgenic product class
inframe_deletion
(Dorafshan et al., 2019)
Mutagen
in vitro construct
(Dorafshan et al., 2019)
Progenitor genotype
Carried in construct
M{Ubi-p63E-ash1.ΔBAH}
Cytology
Description

Ubi-p63E regulatory sequences drive expression of ash1 with the BAH domain deleted; tagged with Tag:StrepII.

(Dorafshan et al., 2019)
Allele components
Component
Use(s)
Regulatory region(s)
Ubi-p63E
Encoded product / tool
ash1
Tagged with
Tag:StrepII
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      The ash122/Df(3L)Exel9011 individuals rescued to adulthood by ash1ΔBAH.Ubi-p63E/ash1ΔBAH.Ubi-p63E and ash1ΔSET.Ubi-p63E/ash1ΔBAH.Ubi-p63E show high and low prevalence, respectively, of homeotic transformation: transformation of the third thoracic segment (T3) to second thoracic segment (T2), including partial transformation of haltere to wing, characterized by the appearance of bristles on the haltere, appearance of hypopleural bristles on T3, and the third leg to second leg transformation manifested by the appearance of apical and pre-apical bristles on the third leg; transformation of posterior abdominal segments to more anterior fate, visible by the partial loss of pigmentation in tergites 5.

      (Dorafshan et al., 2019)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      ash1ΔBAH.Ubi-p63E
      Name Synonyms
      Secondary FlyBase IDs
        References (1)