FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
Allele: Dmel\rheaTS
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General Information
Symbol
Dmel\rheaTS
Species
D. melanogaster
Name
FlyBase ID
FBal0358363
Feature type
allele
Associated gene
Dmel\rhea
Associated Insertion(s)
TI{TI}rheaTS
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
phiC31 integrase
(Lemke et al., 2019)
Progenitor genotype
TI{TI}rheaI-DsRed
(Lemke et al., 2019)
Associated Insertion(s)
TI{TI}rheaTS
Cytology
Description

The RMCE cassette present in TI{TI}rheaI-DsRed has been replaced with sequence that restores the rhea exon that was deleted in TI{TI}rheaI-DsRed and also includes a tension-sensing module inserted after amino acid residue 456. The tension-sensing module comprises the YPet and mCherry fluorescent proteins separated by a mechanosensitive linker peptide (HP, Villin headpiece peptide). This module can report mechanical force in the range of 6-8 piconewtons; an increase in the distance between the two fluorophores should result in a decrease in fluorescence resonance energy transfer (FRET) efficiency.

(Lemke et al., 2019)
Allele components
Component
Use(s)
Encoded product / tool
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      rheaTS
      Name Synonyms
      Secondary FlyBase IDs
        References (1)