FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
Allele: Dmel\Dscam2ABstop
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General Information
Symbol
Dmel\Dscam2ABstop
Species
D. melanogaster
Name
FlyBase ID
FBal0358447
Feature type
allele
Associated gene
Dmel\Dscam2
Associated Insertion(s)
TI{TI}Dscam2ABstop
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
phiC31 integrase
(Tadros et al., 2016)
Progenitor genotype
TI{TI}Dscam2founder
(Tadros et al., 2016)
Associated Insertion(s)
TI{TI}Dscam2ABstop
Cytology
Description

Insertion of sequence (containing three mutations within the alternatively spliced exons 10A and 10B) into the attP site within the TI{TI}Dscam2founder line.

(Tadros et al., 2016)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Dscam2ABstop clones of individual L4 neurons (generated using Scer\FLP1G5.R27G05.Tag:PEST(mOdc)) exhibit a stereotyped dendritic phenotype: an additional branch often extend from one or both of the posterior dendrites and innervate an adjacent cartridge when compared to control adults.

      At 24h APF, Dscam2ABstop clones of L4 neurons (generated using Scer\FLP1G5.R27G05.Tag:PEST(mOdc)) exhibit little (partial mistargeting) or no (complete mistargeting) contact with the target fascicles different than controls.

      (Tadros et al., 2016)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Dscam2ABstop
      Dscam2A+Bstop
      (Tadros et al., 2016)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)