shg in which 60aa within the shg conserved serine cluster is deleted and tagged at the C-terminal end with GFP and fused to α-Cat has been knocked in to a founder shg knockout line containing a attP site.
abnormal size | somatic clone | third instar larval stage
lethal (with shg2)
lethal - all die during embryonic stage
adherens junction | somatic clone | third instar larval stage
embryonic/first instar larval cuticle | embryonic stage
wing disc | somatic clone | third instar larval stage
Third instar larval wing disc clones of shgΔβS.α-Cat.GFP are small, rounded and fail to form discernible adherens junctions.
shgΔβS.α-Cat.GFP homozygous embryos exhibit cuticle defects.