FB2026_03 , released September 17, 2026
Allele: Dmel\snoRNA:Ψ28S-1153+t1.7
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General Information
Symbol
Dmel\snoRNA:Ψ28S-1153+t1.7
Species
D. melanogaster
Name
FlyBase ID
FBal0358996
Feature type
allele
Associated gene
Dmel\snoRNA:Ψ28S-1153
Associated Insertion(s)
Carried in Construct
P{snoRNA:Ψ28S-11531.7}
Key Links
Transgenic product class
genomic_DNA
(Soulé et al., 2020)
wild_type
(Soulé et al., 2020)
Mutagen
Nature of the Allele
Transgenic product class
genomic_DNA
(Soulé et al., 2020)
wild_type
(Soulé et al., 2020)
Mutagen
in vitro construct
(Soulé et al., 2020)
Progenitor genotype
Carried in construct
P{snoRNA:Ψ28S-11531.7}
Cytology
Description

A DNA-fragment of 1723 bp, comprising the putative genomic and regulatory region of 3 adjacent snoRNAs: snoRNA:Ψ28S-1153, snoRNA:2R:9445205 and snoRNA:2R:9445410.

(Soulé et al., 2020)
Allele components
Component
Use(s)
Regulatory region(s)
snoRNA:Ψ28S-1153
Encoded product / tool
snoRNA:Ψ28S-1153
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      In an otherwise control background, snoRNA:Ψ28S-1153+t1.7 induces increased female lifespan and resistance to desiccation, as compared to controls.

      snoRNA:Ψ28S-1153+t1.7 rescues the a) decreased lifespan, b) sensitivity to desiccation, as well as the c) increased numbers of enterocytes (in both 7-days old and 40-days old individuals) and the d) decreased ploidy/endoreplication in the gut, of Df(2R)F4 homozygous females.

      (Soulé et al., 2020)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      snoRNA:Ψ28S-1153+t1.7
      Name Synonyms
      Secondary FlyBase IDs
        References (2)