12kb genomic fragment that encompasses the trr transcription unit and its regulatory elements. A C2398A amino acid substitution has been introduced into the open reading frame; this mutation results in a catalytically deficient protein when analysed in vitro.
trrC2398A eggs exhibit normal oocyte-to-embryo transition, as they initiate embryogenesis at a similar rate to that of wild-type controls, despite a slight reduction in hatching rate.
