FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Hsap\RELAunc-4-AD
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General Information
Symbol
Hsap\RELAunc-4-AD
Species
H. sapiens
Name
FlyBase ID
FBal0360290
Feature type
allele
Associated gene
Hsap\RELA
Associated Insertion(s)
TI{2A-p65(AD)::Zip+}unc-4AD
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
phiC31 integrase
(Lacin et al., 2020)
Progenitor genotype
TI{TI}unc-4FRT
(Lacin et al., 2020)
Associated Insertion(s)
TI{2A-p65(AD)::Zip+}unc-4AD
Cytology
Description

2A-p65(AD)::Zip+ is introduced into the attP site in the TI{TI}unc-4FRT progenitor. The Trojan insertion introduces a stop codon, truncating the unc-4 protein after its first exon.

(Lacin et al., 2020)
Allele components
Component
Use(s)
Inserted element
TI{2A-p65(AD)::Zip+}
Encoded product / tool
p65(AD)::Zip+
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      distribution deduced from reporter (Gal4 UAS)
      Stage
      Tissue/Position (including subcellular localization)
      Reference
      third instar larval stage

      Comment: when combined with P{Tub-GAL4DBD.D}

      (Lacin et al., 2020)
      larval central nervous system

      Comment: when combined with P{Tub-GAL4DBD.D}

      (Lacin et al., 2020)
      U neuron

      Comment: when combined with Mi{Trojan-GAL4DBD.2}VGlutMI04979-TG4DBD.2

      (Lacin et al., 2020)
      adult stage
      mechanosensory neuron of leg chordotonal organ

      Comment: when combined with Mi{Trojan-GAL4DBD.0}ChATMI04508-TG4DBD.0

      (Lacin et al., 2020)
      sensory neuron of campaniform sensillum

      Comment: when combined with Mi{Trojan-GAL4DBD.0}ChATMI04508-TG4DBD.0

      (Lacin et al., 2020)
      adult motor neuron of neck

      Comment: when combined with Mi{Trojan-GAL4DBD.2}VGlutMI04979-TG4DBD.2

      (Lacin et al., 2020)
      DLM motor neuron

      Comment: when combined with Mi{Trojan-GAL4DBD.2}VGlutMI04979-TG4DBD.2

      (Lacin et al., 2020)
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      unc-4
      (Lacin et al., 2020)
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Hsap\RELAunc-4-AD
      unc-4AD
      (Lacin et al., 2020)
      Name Synonyms
      Secondary FlyBase IDs
        References (3)