FB2026_02 , released June 18, 2026
Allele: Dmel\Irp-1AKO
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General Information
Symbol
Dmel\Irp-1AKO
Species
D. melanogaster
Name
FlyBase ID
FBal0360847
Feature type
allele
Associated gene
Dmel\Irp-1A
Associated Insertion(s)
TI{TI}Irp-1AKO
Carried in Construct
Also Known As
IRP1AKO
Key Links
Genomic Maps

Allele class

amorphic allele - molecular evidence

Mutagen
Nature of the Allele
Allele class

amorphic allele - molecular evidence

(Huynh et al., 2019)
Mutagen
CRISPR/Cas9
(Huynh et al., 2019)
gene targeting by homologous recombination
(Huynh et al., 2019)
Progenitor genotype
Associated Insertion(s)
TI{TI}Irp-1AKO
Cytology
Description

The endogenous Irp-1A locus has been deleted and replaced by a loxP site.

(Huynh et al., 2019)
Allele components
Component
Use(s)
Also carries
loxP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
deletion
3R:22,721,188..22,724,819 [-]
Comment:

A 3632bp deletion that removes Irp-1A. A loxP site was inserted in its place.

(Huynh and King-Jones, 2020.8.14)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 1 )
      Disease
      Evidence
      References
      model of  porphyria
      CEA
      (Huynh et al., 2019)
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      IRP1AKO
      (Huynh et al., 2020, Huynh et al., 2019)
      Irp-1AKO
      Name Synonyms
      Secondary FlyBase IDs
        References (3)